top of page
広島大学
大学院統合生命科学研究科
分子栄養学研究室
Last Updated:2023/11/25
PUBLICATION
-
Exogenous Penicillium camemberti lipase preparation exerts prebiotic-like effects by increasing cecal Bifidobacterium and Lactobacillus abundance in rats. Fermentation, 9: 227, 2023. , Jia H, Ando C, Kato H, Kumrungsee T, Kato N, Kimoto A, Fukuda S, Kuroda M, Nishio K, and Yamaguchi S: Yang Y
-
The modification of buckwheat polyphenols by different pretreatments and complexation, and its application in oat flour model. Food Bioscience, 56: 103133, 2023.Liu X, Wang L, Li C, Li X, Kumrungsee T, Zhai X, Zhou Z, Cao R.
-
Effects of processings and complexation on solubility, antioxidant and antibacterial properties of buckwheat polyphenols. Food and Bioprocess Technology, https://doi.org/10.1007/s11947-023-03217-8, 2023.Liu X, Ma Q, Sun Y, Ju W, Kumrungsee T, Zhou Z, Wang L, and Cao R:
-
Effect of pressure cooking on phenolic compounds of quinoa. Grain & Oil Science and Technology, 6: 127-134, 2023.Ma Q, Li Z, Kumrungsee T, Huang W, and Cao R:
-
Serum amyloid A3 promoter-driven luciferase activity enables visualization of diabetic kidney disease. International Journal of Molecular Sciences, 23: 899, 2022.Saliu TP, Yazawa N, Hashimoto K, Miyata K, Kudo A, Horii M, Kamesawa M, Kumrungsee T, and Yanaka N:
-
Satellite cell content and muscle regeneration in a mouse model of NAFLD. Nutrition, 96:111570, 2022.Saliu TP, Kumrungsee T, Mitsumoto K, Chen S, and Yanaka N:
-
Emerging cardioprotective mechanisms of vitamin B6: a narrative review. European Journal of Nutrition, 61:605-13, 2022.Kumrungsee T, Zhang P, Yanaka N, Suda T, and Kato N:
-
Aspergillus-derived cellulase preparation exhibits prebiotic-like effects on gut microbiota in rats. Fermentation, 8: 71, 2022.Yang Y, Kumrungsee T, Kato N, Fukuda S, Kuroda M, and Yamaguchi S:
-
Comparative study on molecular mechanism of diabetic myopathy in two different types of streptozotocin-induced diabetic models. Life Sciences, 288: 120183, 2022.Saliu TP, Kumrungsee T, Miyata K, Tominaga H, Yazawa N, Hashimoto K, Kamesawa M, and Yanaka N:
-
Rhabdomyolysis after consumption of freshwater fish (Neolissochilus soroides). Wilderness & Environmental Medicine, 32: 410-3, 2021.Chartkul M, Petvicharn KN, Kumrungsee T, Jiranantakan T, and Chomchai S:
-
Fermented date residue extract mix containing gamma-aminobutyric acid augments the immune function of mouse splenocytes. Bioscience, Biotechnology, and Biochemistry, 85: 1753-8, 2021.Hattori K, Yamamoto Y, Fujii S, Kumrungsee T, Hasegawa M, Yoshida A, Suzuki T, and Sambongi Y:
-
Liver choline metabolism and gene expression in choline-deficient mice offspring differ with gender. Bioscience, Biotechnology, and Biochemistry, 85: 447-51, 2021.Miyachi Y, Akiyama K, Tsukuda Y, Kumrungsee T, and Yanaka N:
-
Supplemental Aspergillus lipase and protease preparations display powerful bifidogenic effects and modulate the gut microbiota community of rats. Fermentation, 7: 294, 2021.Yang Y, Kumrungsee T, Kato N, Fukuda S, Kuroda M, and Yamaguchi S:
-
Characterization of recombinant murine GDE4 and GDE7, enzymes producing lysophosphatidic acid and/or cyclic phosphatidic acid. The Journal of Biochemistry, 170(6), 713-727, 2021.Tserendavga, B., Ohshima, N., Fujita, C., Yuzawa, K., Ohshima, M., Yanaka, N., Yoji, M., Izumi, T:
-
Satellite cells exhibit decreased numbers and impaired functions on single myofibers isolated from vitamin B6-deficient mice. Nutrients, 13: 4531, 2021.Komaru T, Yanaka N, and Kumrungsee T:
-
Molecular docking and pharmacokinetic studies of phytocompounds from Nigerian Medicinal Plants as promising inhibitory agents against SARS-CoV-2 methyltransferase (nsp16). Journal of Genetic Engineering and Biotechnology, 19(1), 1-12, 2021.Saliu, T. P., Umar, H. I., Ogunsile, O. J., Okpara, M. O., Yanaka, N., & Elekofehinti, O. O.:
-
Dietary GABA and its combination with vigabatrin mimic calorie restriction and induce antiobesity-like effects in lean mice. Journal of Functional Foods, 78: 104367, 2021.Sato K, Komaru T, Arima T, Jardson C, Yanaka N, and Kumrungsee T:
-
Potential role of vitamin B6 in ameliorating the severity of COVID-19 and its complications. Frontiers in Nutrition, 7: 562051, 2020.Kumrungsee T, Zhang P, Chartkul M, Yanaka N, and Kato N:
-
Increased glucose metabolism in Arid5b−/− skeletal muscle is associated with the down-regulation of TBC1 domain family member 1 (TBC1D1). Biological Research, 53, 1-14, 2020.Okazaki, Y., Murray, J., Ehsani, A., Clark, J., Whitson, R. H., Hirose, L., Yanaka N. & Itakura, K. :
-
Mungbean seed coat water extract inhibits inflammation in LPS-induced acute liver injury mice and LPS-stimulated RAW 246.7 macrophages via the inhibition of TAK1/IκBα/NF-κB. Journal of Food Science and Technology, 57: 2659-68, 2020.Sae-Tan S, Kumrungsee T, and Yanaka N:
-
Low-dose ethanol has impacts on plasma levels of metabolites relating to chronic disease risk in SAMP8 mice. Journal of Nutritional Science and Vitaminology, 66: 553-60, 2020.Fu C, Yang Y, Kumrungsee T, Kimoto A, Izu H, and Kato N:
-
Dietary GABA induces endogenous synthesis of a novel imidazole peptide homocarnosine in mouse skeletal muscles. Amino Acids, 52: 743-53, 2020.Kumrungsee T, Arima T, Sato K, Komaru T, Sato M, Oishi Y, Egusa A, and Yanaka N:
-
Novel metabolic disturbances in marginal vitamin B6-deficient rat heart. Journal of Nutritional Biochemistry, 65: 26-34, 2019.Kumrungsee T, Nirmagustina DE, Arima T, Onishi K, Sato K, Kato N, and Yanaka N:
-
GDE5 inhibition accumulates intracellular glycerophosphocholine and suppresses adipogenesis at a mitotic clonal expansion stage. American Journal of Physiology-Cell Physiology, 316: C162-C174, 2019Okazaki Y, Nakamura K, Takeda S, Yoshizawa I, Yoshida F, Ohshima N, Izumi T, Klein JD, Kumrungsee T, Sands JM, and Yanaka N:
-
High-dose D-glucosamine consumption increases serum and cecum levels of ammonia and ethanol and causes bacterial overgrowth in rats. Food Science and Technology Research, 25: 107-113, 2019.Nirmagustina DE, Khedara A, Benouchenne D, Boubekri K, Yang Y, Suidasari S, Kumrungsee T, and Kato N:
-
The serum amyloid A3 promoter-driven luciferase reporter mice is a valuable tool to image early renal fibrosis development and shows the therapeutic effect of glucosyl-hesperidin treatment. Scientific Reports, 9: 14101, 2019.Kumrungsee T, Kariya T, Hashimoto K, Koyano T, Yazawa N, Hashimoto T, Sanada Y, Matsuyama M, Sotomaru Y, Sakurai H, van de Loo FA:
-
GDE5 inhibition accumulates intracellular glycerophosphocholine and suppresses adipogenesis at a mitotic clonal expansion stage. Am. J. Physiol.- Cell Physiol., pp. C162–C174 2019.Okazaki Y, Nakamura K, Takeda S, Yoshizawa I, Yoshida F, Ohshima N, Izumi T, Klein JD, Kumrungsee T, Sands JM, and Yanaka N:
-
Yang B, Kumoto T, Arima T, Nakamura M, Sanada Y, Kumrungsee T, Sotomaru Y, Shimada M, and Yanaka N: Transgenic mice specifically expressing amphiregulin in white adipose tissue showed less adipose tissue mass. Genes Cells, 23: 136–145. 2018.
-
Zhang P, Suda T, Kumrungsee T, Yanaka N, and Kato, N: Novel preventive mechanisms of vitamin B6 against inflammation, inflammasome, and chronic diseases. In: Molecular Nutrition of Vitamins, edited by Patel V.B. Elsevier Science, Amsterdam, in press.
-
Yang Y, Kameda T, Aoki H, Nirmagustina DE, Iwamoto A, Kato N, Yanaka N, Okazaki Y, and Kumrungsee T: The effects of tempe fermented with Rhizopus microsporus, Rhizopus oryzae, or Rhizopus stolonifer on the colonic luminal environment in rats. Journal of Functional Foods, 49: 162-167. 2018.
-
Kameda T, Aoki H, Yang Y, Nirmagustina DE, Iwamoto I, Kumrungsee T, Kato N, and Yanaka N: Beneficial Effects of Dietary Tempeh Prepared with Rhizopus stolonifer on Liver Function in Rats Fed with High-Fat Diet. J Nutr Sci Vitaminol. (Tokyo), 64: 379-383. 2018.
-
Kameda T, Aoki H, Yanaka N, Kumrungsee T, and Kato N: Production of isoflavone aglycone-enriched tempeh by Rhizopus stolonifer. Food. Sci. Technol. Res., 24: 493-499. 2018.
-
Nirmagustina DE, Yang Y, Yanaka N, Kumrungsee T, and Kato N: Gender difference and dietary supplemental vitamin B6: impact on colon luminal environment. J. Nutr. Sci. Vitaminol. (Tokyo), 64:116-128. 2018.
-
Nakamura M, Kumrungsee T, Sakuma T, Yamamoto T, and Yanaka N: TALEN-mediated targeted editing of the GDE5 gene suppresses fibroblastic cell proliferation. Biosci. Biotechnol. Biochem., 81: 2164-2167. 2017.
-
Mitsumoto K, Watanabe R, Nakao K, Yonenaka H, Hashimoto T, Kato N, Kumrungsee T, and Yanaka N: Time-course microarrays reveal early activation of the immune transcriptome in a choline-deficient mouse model of liver injury. Life Sci., 184: 103-111. 2017.
-
Suidasari S, Uragami S, Yanaka N, and Kato N: Dietary vitamin B6 modulates the gene expression of myokines, Nrf2-related factors, myogenin and HSP60 in the skeletal muscle of rats. Exp. Ther. Med., 2017 14: 3239-3246. 2017.
-
Kumrungsee T, Nirmagustina DE, Kato N, Yanaka N, and Lai HC: Vitamin B6: a heart-protective molecule through a novel mechanism of increasing histidine-related compounds. In A. Mendez-Vilas (Ed.), Science within Food: Up-to-date Advances on Research and Educational Ideas. Formatex Research Center, Formatex Research Center. 292-299, 2017.
-
Limpimwong W, Kumrungsee T, Nakao K, Yanaka N, and Masubon T: Rice bran wax oleogel: A potential margarine replacement and its digestibility effect in rats fed a high-fat diet. J. Funct. Foods, 39: 250-256, 2017.
-
Tsujita N, Kuwahara H, Koyama H, Yanaka N, Arakawa K, and Kuniyoshi H: Molecular characterization of aspartylglucosaminidase, a lysosomal hydrolase upregulated during strobilation in the moon jellyfish, Aurelia aurita. Biosci. Biotechnol. Biochem., 81: 938-950. 2017.
-
Yoshida I, Ito C, Matsuda S, Tsuji A, Yanaka N, and Yuasa K: Alisol B, a triterpene from Alismatis rhizoma (dried rhizome of Alisma orientale), inhibits melanin production in murine B16 melanoma cells. Biosci. Biotechnol. Biochem., 81: 534-540. 2017.
-
Sanada Y, Yamamoto T, Satake R, Yamashita A, Kanai S, Kato N, van de Loo FA, Nishimura F, Scherer PE, and Yanaka N: Serum amyloid A3 gene expression in adipocytes is an indicator of the interaction with macrophages. Sci. Rep., 6: 38697. 2016.
-
Hashimoto T, Yang B, Okazaki Y, Yoshizawa I, Kajihara K, Kato N, Wada M, and Yanaka N: Time course analysis of skeletal muscle pathology of GDE5 transgenic mouse. PLoS One, 11: e0163299, 2016.
-
Nakagawa Y, Sakuma T, Nishimichi N, Yokosaki Y, Yanaka N, Takeo T, Nakagata N, and Yamamoto T: Ultra-superovulation for the CRISPR-Cas9-mediated production of gene-knockout, single-amino-acid-substituted, and floxed mice. Biol. Open, 5: 1142-1148, 2016.
-
Kawai T, Yanaka N, Richards JS, and Shimada M: De novo-synthesized retinoic acid in ovarian antral follicles enhances FSH-mediated ovarian follicular cell differentiation and female fertility. Endocrinology, 157: 2160-2172, 2016.
-
Suidasari S, Stautemas J, Uragami S, Yanaka N, Derave W, and Kato N: Carnosine content in skeletal muscle is dependent on vitamin B6 status in rats. Front. Nutr., 2: 39. 2016.
-
Kaji T, Hijikata A, Ishige A, Kitami T, Watanabe T, Ohara O, Yanaka N, Okada M, Shimoda M, Taniguchi M, and Takemori T: CD4 memory T cells develop and acquire functional competence by sequential cognate interactions and stepwise gene regulation. Int. Immunol., 28: 267-282. 2016.
-
Ohshima N, Kudo T, Yamashita Y, Mariggiò S, Araki M, Honda A, Nagano T, Isaji C, Kato N, Corda D, Izumi T, and Yanaka N: New members of the mammalian glycerophosphodiester phosphodiesterase family: GDE4 and GDE7 produce lysophosphatidic acid by lysophospholipase D activity. J. Biol. Chem., 290: 4260-4271, 2015.
-
Watanabe D, Kanzaki K, Kuratani M, Matsunaga S, Yanaka N, and Wada M: Contribution of impaired myofibril and ryanodine receptor function to prolonged low-frequency force depression after in situ stimulation in rat skeletal muscle. J. Muscle Res. Cell Motil., 36: 275-286, 2015.
-
Suidasari S, Hasegawa T, Yanaka N, and Kato N: Dietary supplemental vitamin B6 increases carnosine and anserine concentrations in the heart of rats. Springerplus, 4: 280, 2015.
-
Corda D, Mosca MG, Ohshima N, Grauso L, Yanaka N, and Mariggiò S: The emerging physiological roles of the glycerophosphodiesterase family. FEBS J., 281: 998-1016, 2014.
-
Kanzaki K, Kuratani M, Matsunaga S, Yanaka N, and Wada M: Three calpain isoforms are autolyzed in rat fast-twitch muscle after eccentric contractions. J. Muscle Res. Cell Motil., 35: 179-189, 2014.
-
Zhang P, Suidasari S, Hasegawa T, Yanaka N, and Kato N: Vitamin B6 activates p53 and elevates p21 gene expression in cancer cells and the mouse colon. Oncol. Rep., 31: 2371-2376, 2014.
-
Haraguchi T, Kayashima T, Okazaki Y, Inoue J, Mineo S, Matsubara K, Sakaguchi E, Yanaka N, and Kato N: Cecal succinate elevated by some dietary polyphenols may inhibit colon cancer cell proliferation and angiogenesis. J. Agric. Food Chem., 62: 5589-5594, 2014.
-
Sanada Y, Kumoto T, Suehiro H, Yamamoto T, Nishimura F, Kato N, and Yanaka N: IκB kinase epsilon expression in adipocytes is upregulated by interaction with macrophages. Biosci. Biotechnol. Biochem., 78: 1357-1362, 2014.
-
Sanada Y, Kumoto T, Suehiro H, Nishimura F, Kato N, Hata Y, Sorisky A, and Yanaka N: RASSF6 expression in adipocytes is down-regulated by interaction with macrophages. PLoS One, 8: e61931, 2013.
-
Zhang P, Suidasari S, Hasegawa T, Yanaka N, and Kato N: High concentrations of pyridoxal stimulate the expression of IGFBP1 in HepG2 cells through upregulation of the ERK/c-Jun pathway. Mol. Med. Rep., 8: 973-978, 2013.
-
Toya K, Hirata A, Ohata T, Sanada Y, Kato N, and Yanaka N: Regulation of colon gene expression by vitamin B6 supplementation. Mol. Nut. Food Res., 56: 641-652, 2012.
-
Kayashima T, Tanaka K, Okazaki Y, Matsubara K, Yanaka N, and Kato N: Consumption of vitamin B6 reduces colonic damage and protein expression of HSP70 and HO-1, the anti-tumor targets, in rats exposed to 1,2-dimethylhydrazine. Oncol. Lett., 2: 1243-1246, 2011.
-
Masisi K, Suidasari S, Zhang P, Okazaki Y, Yanaka N, and Kato N: Comparative study on the responses of concentrations of B6-vitamers in several tissues of mice to the dietary level of pyridoxine. J. Nutr. Sci. Vitaminol. (Tokyo), 58: 446-451, 2012.
-
Okazaki Y, Utama Z, Suidasari S, Zhang P, Yanaka N, Tomotake H, Sakaguchi E, and Kato N: Consumption of vitamin B(6) reduces fecal ratio of lithocholic acid to deoxycholic acid, a risk factor for colon cancer, in rats fed a high-fat diet. J. Nutr. Sci. Vitaminol. (Tokyo), 58: 366-370, 2012.
-
Yanaka N, Ohata T, Toya K, Kanda M, Hirata A, and Kato N: Vitamin B6 suppresses serine protease inhibitor 3 expression in the colon of rats and in TNF-α-stimulated HT-29 cells. Mol. Nutr. Food Res., 55: 635-643, 2011.
-
Yanaka N, Kanda M, Toya K, Suehiro H, and Kato N: Vitamin B6 regulates mRNA expression of peroxisome proliferator-activated receptor-γ target genes. Exp. Ther. Med., 2: 419-424, 2011.
-
Haraguchi T, Yanaka N, Eguchi Y, Kudo T, Hirata A, and Kato N: Fish oil feeding up-regulates the expression of 5-aminolevulinate synthase 2 mRNA in rat brain. Biosci. Biotechnol. Biochem., 75: 1383-1385, 2011.
-
Dairaku I, Han Y, Yanaka N, and Kato N: Inhibitory effect of curcumin on IMP dehydrogenase, the target for anticancer and antiviral chemotherapy agents. Biosci. Biotechnol. Biochem., 74: 185-187, 2010.
-
Okazaki Y, Ohshima N, Yoshizawa I, Kamei Y, Mariggiò S, Okamoto K, Maeda M, Nogusa Y, Fujioka Y, Izumi T, Ogawa Y, Shiro Y, Wada M, Kato N, Corda D, and Yanaka N: A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism. J. Biol. Chem., 285: 27652-27663, 2010.
-
Kanzaki K, Kuratani M, Mishima T, Matsunaga S, Yanaka N, Usui S, and Wada M: The effects of eccentric contraction on myofibrillar proteins in rat skeletal muscle. Eur. J. Appl. Physiol., 110: 943-952, 2010.
-
Hirata T, Fujii M, Akita K, Yanaka N, Ogawa K, Kuroyanagi M, and Hongo D: Identification and physiological evaluation of the components from citrus fruits as potential drugs for anti-corpulence and anticancer. Bioorg. Med. Chem., 17: 25-28, 2009.
-
Corda D, Kudo T, Zizza P, Iurisci C, Kawai E, Kato N, Yanaka N, and Mariggiò S: The developmentally regulated osteoblast phosphodiesterase GDE3 is glycerophosphoinositol-specific and modulates cell growth. J. Biol. Chem., 284: 24848-24856, 2009.
-
Yanaka N, Kaseda Y, Tanaka A, Nogusa Y, Sumiyoshi N, and Kato N: Generation of a zinc finger protein ZPR1 mutant that constitutively interacted with translation elongation factor 1alpha. Biosci. Biotechnol. Biochem., 73: 2809-2811, 2009.
-
Yanaka N, Nogusa Y, Fujioka Y, Yamashita Y, and Kato N: Involvement of membrane protein GDE2 in retinoic acid-induced neurite formation in Neuro2A cells. FEBS Lett., 581: 712-718, 2007.
-
Mizushina Y, Dairaku I, Yanaka N, Takeuchi T, Ishimaru C, Sugawara F, Yoshida H, and Kato N: Inhibitory action of polyunsaturated fatty acids on IMP dehydrogenase. Biochimie, 89: 581-590, 2007.
-
Yanaka N: Mammalian glycerophosphodiester phosphodiesterases. Biosci. Biotechnol. Biochem., 71: 1811-1818, 2007.
-
Tomotake H, Yamamoto N, Yanaka N, Ohinata H, Yamazaki R, Kayashita J, and Kato N: High protein buckwheat flour suppresses hypercholesterolemia in rats and gallstone formation in mice by hypercholesterolemic diet and body fat in rats because of its low protein digestibility. Nutrition, 22: 166-173, 2006.
-
Nogusa Y, Yanaka N, Sumiyoshi N, Takeda K, and Kato N: Expression of zinc finger protein ZPR1 mRNA in brain is up-regulated in mice fed a high-fat diet. Int. J. Mol. Med., 17: 491-496, 2006.
-
Haraguchi T, Yanaka N, Nogusa Y, Sumiyoshi N, Eguchi Y, and Kato N: Expression of ADP-ribosylation factor-like protein 8B mRNA in the brain is down-regulated in mice fed a high-fat diet. Biosci. Biotechnol. Biochem., 70: 1798-1802, 2006.
-
Hashimoto T, Fukunari A, Yamada I, Yanaka N, Chen D, and Kato N: Y-700, a novel inhibitor of xanthine oxidase, suppresses the development of colon aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine-treated mice. Biosci. Biotechnol. Biochem., 69: 209-211, 2005.
-
Nogusa Y, Yanaka N, Sumiyoshi N, Kaseda Y, Tsuboyama-Kasaoka N, Ezaki O, and Kato N: Short-term feeding of fish oil down-regulates the expression of pyruvate dehydrogenase E1 alpha subunit mRNA in mouse brain. Biosci. Biotechnol. Biochem., 69: 301-306, 2005.
-
Komatsu S, Isobe M, Yanaka N, and Kato N: A high-fat diet enhances the inhibitory effect of dietary vitamin B6 on colon cell proliferation in mice. Oncol. Rep., 14: 265-269, 2005.
-
Yanaka N, Koyama TA, Komatsu S, Nakamura E, Kanda M, and Kato N: Vitamin B6 suppresses NF-kappaB activation in LPS-stimulated mouse macrophages. Int. J. Mol. Med., 16: 1071-1075, 2005.
-
Nogusa Y, Fujioka Y, Komatsu R, Kato N, and Yanaka N: Isolation and characterization of two serpentine membrane proteins containing glycerophosphodiester phosphodiesterase, GDE2 and GDE6. Gene, 337: 173-179, 2004.
-
Zhaorigetu S, Yanaka N, Sasaki M, Watanabe H, and Kato N: Silk protein, sericin, suppresses DMBA-TPA-induced mouse skin tumorigenesis by reducing oxidative stress, inflammatory responses and endogenous tumor promoter TNF-alpha. Oncol. Rep., 10: 537-543, 2003.
-
Komatsu S, Yanaka N, Matsubara K, and Kato N: Antitumor effect of vitamin B6 and its mechanisms. Biochim. Biophys. Acta.- Proteins and Proteomics, 1647: 127-130, 2003.
-
Yanaka N, Kurosawa Y, Minami K, Kawai E, and Omori K: cGMP-phosphodiesterase activity is up-regulated in response to pressure overload of rat ventricles. Biosci. Biotechnol. Biochem., 67: 973-979, 2003.
-
Yanaka N, Imai Y, Kawai E, Akatsuka H, Wakimoto K, Nogusa Y, Kato N, Chiba H, Kotani E, Omori K, and Sakurai N: Novel membrane protein containing glycerophosphodiester phosphodiesterase motif is transiently expressed during osteoblast differentiation. J. Biol. Chem., 278: 43595-43602, 2003.
-
Zhaorigetu S, Yanaka N, Sasaki M, Watanabe H, and Kato N: Inhibitory effects of silk protein, sericin on UVB-induced acute damage and tumor promotion by reducing oxidative stress in the skin of hairless mouse. J. Photochem. Photobiol. B, 71: 11-17, 2003.
-
Michibata H, Yanaka N, Kanoh Y, Okumura K, and Omori K: Human Ca2+/calmodulin-dependent phosphodiesterase PDE1A: novel splice variants, their specific expression, genomic organization, and chromosomal localization. Biochim. Biophys. Acta.-Gene Structure and Expression, 1517: 278-287, 2001.
-
Wakimoto K, Kuro-o M, Yanaka N, Komuro I, Nabeshima YI, and Imai Y: Expression of Na+/Ca(2+) exchanger (NCX1) gene in the developmental mouse embryo and adult mouse brain. Comp. Biochem. Physiol. B Biochem. Mol. Biol., 130: 191-198, 2001.
-
Yuasa K, Michibata H, Omori K, and Yanaka N: Identification of a conserved residue responsible for the autoinhibition of cGMP-dependent protein kinase Ialpha and beta. FEBS Lett., 466: 175-178, 2000.
-
Yuasa K, Omori K, and Yanaka N: Binding and phosphorylation of a novel male germ cell-specific cGMP-dependent protein kinase-anchoring protein by cGMP-dependent protein kinase Ialpha. J. Biol. Chem., 275: 4897-4905, 2000.
-
Yanaka N, Kobayashi K, Wakimoto K, Yamada E, Imahie H, Imai Y, and Mori C: Insertional mutation of the murine kisimo locus caused a defect in spermatogenesis. J. Biol. Chem., 275: 14791-14794, 2000.
-
Yuasa K, Omori K, and Yanaka N: Specific domain of cGMP-dependent protein kinase Ibeta but not Ialpha functions as a transcriptional activator in yeast. IUBMB Life, 49: 17-22, 2000.
-
Wakimoto K, Kuro-O M, Yanaka N, Omori K, Komuro I, Imai Y, and Nabeshima Y: Isolation and characterization of Na+/Ca2+ exchanger gene and splicing isoforms in mice. DNA Seq., 11: 75-81, 2000.
-
Wakimoto K, Kobayashi K, Kuro-O M, Yao A, Iwamoto T, Yanaka N, Kita S, Nishida A, Azuma S, Toyoda Y, Omori K, Imahie H, Oka T, Kudoh S, Kohmoto O, Yazaki Y, Shigekawa M, Imai Y, Nabeshima Y, and Komuro I: Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat. J. Biol. Chem., 275: 36991-36998, 2000.
-
Kotera J, Fujishige K, Imai Y, Kawai E, Michibata H, Akatsuka H, Yanaka N, and Omori K: Genomic origin and transcriptional regulation of two variants of cGMP-binding cGMP-specific phosphodiesterases. Eur. J. Biochem., 262: 866-873, 1999.
-
Fujishige K, Kotera J, Yanaka N, Akatsuka H, and Omori K: Alteration of cGMP metabolism during chondrogenic differentiation of chondroprogenitor-like EC cells, ATDC5. Biochim. Biophys. Acta. - Molecular Cell Research, 1452: 219-227, 1999.
-
Yuasa K, Michibata H, Omori K, and Yanaka N: A novel interaction of cGMP-dependent protein kinase I with troponin T. J. Biol. Chem., 274: 37429-37434, 1999.
-
Yanaka N, Kotera J, Ohtsuka A, Akatsuka H, Imai Y, Michibata H, Fujishige K, Kawai E, Takebayashi S, Okumura K, and Omori K: Expression, structure and chromosomal localization of the human cGMP-binding cGMP-specific phosphodiesterase PDE5A gene. Eur. J. Biochem., 255: 391-399, 1998.
-
Kotera J, Fujishige K, Akatsuka H, Imai Y, Yanaka N, and Omori K: Novel alternative splice variants of cGMP-binding cGMP-specific phosphodieserase. J. Biol. Chem., 273: 26982-26990, 1998.
-
Yanaka N, Akatsuka H, Kawai E, and Omori K: 1,25-Dihydroxyvitamin D3 upregulates natriuretic peptide receptor-C expression in mouse osteoblasts. Am. J. Physiol.- Endo., 275: E965-E973, 1998.
-
Yanaka N, Kotera J, and Omori K: Isolation and characterization of the 5'-flanking regulatory region of the human natriuretic peptide receptor C gene. Endocrinology, 139: 1389-1400, 1998.
-
Fujishige K, Yanaka N, Akatsuka H, and Omori K: Localization of clearance receptor in rat lung and trachea: association with chondrogenic differentiation. Am. J. Physiol.-Lung, 274: L425-L431, 1998.
-
Koguchi Y, Asai Y, Suzuki S, Nishio M, Yanaka N, Omori K, Ohnuki T, and Komatsubara S: TMC-49A, a novel transcriptional up-regulator of low density lipoprotein receptor, produced by Streptomyces sp. AS1345. J. Antibiot. (Tokyo), 51: 107-111, 1998.
-
Kotera J, Yanaka N, Fujishige K, Imai Y, Akatsuka H, Ishizuka T, Kawashima K, and Omori K: Expression of rat cGMP-binding cGMP-specific phosphodiesterase mRNA in Purkinje cell layers during postnatal neuronal development. Eur. J. Biochem., 249: 434-442, 1997.
-
Yanaka N, Akatsuka H, and Omori K: Protein kinase C activation down-regulates natriuretic peptide receptor C expression via transcriptional and post-translational pathways. FEBS Lett., 418: 333-336, 1997.
-
Yanaka N, Kotera J, Taguchi I, Sugiura M, Kawashima K, and Omori K: Structure of the 5'-flanking regulatory region of the mouse gene encoding the clearance receptor for atrial natriuretic peptide. Eur. J. Biochem., 237: 25-34, 1996.
-
Kobayashi M, Yanaka N, Nagasawa T, and Yamada H: Primary structure of an aliphatic nitrile-degrading enzyme, aliphatic nitrilase, from Rhodococcus rhodochrous K22 and expression of its gene and identification of its active site residue. Biochemistry, 31: 9000-9007. 1992.
-
Kobayashi M, Komeda H, Yanaka N, Nagasawa T, and Yamada H: Nitrilase from Rhodococcus rhodochrous J1. Sequencing and overexpression of the gene and identification of an essential cysteine residue. J. Biol. Chem., 267: 20746-20751, 1992.
-
Kobayashi M, Yanaka N, Nagasawa T, and Yamada H: Hyperinduction of an aliphatic nitrilase by Rhodococcus rhodochrous K22. FEMS Microbiology Lett., 77: 121-123, 1991.
-
Kobayashi M, Yanaka N, Nagasawa T, and Yamada H: Purification and characterization of a novel nitrilase of Rhodococcus rhodochrous K22 that acts on aliphatic nitriles. J. Bacteriol., 172: 4807-4815, 1990.
-
Kobayashi M, Yanaka N, Nagasawa T, and Yamada H: Nitrilase-catalyzed production of pyrazinoic acid, an antimycobacterial agent, from cyanopyrazine by resting cells of Rhodococcus rhodochrous J1. J. Antibiot. (Tokyo), 43: 1316-1320, 1990.
-
Kobayashi M, Yanaka N, Nagasawa T, and Yamada H: Monohydrolysis of an aliphatic dinitrile compound by nitrilase from Rhodococcus rhodochrous K22. Tetrahedron, 46: 5587-5590, 1990.
-
Kobayashi M, Nagasawa T, Yanaka N, and Yamada H: Nitrilase-catalyzed production of para-aminobenzoic acid from para-aminobenzonitorile with Rhodococcus rhodochrous J1. Biotechnol. Lett., 11: 27-30, 1989.
bottom of page